INSIGHT ON ECDNA-MEDIATED TUMORIGENESIS AND DRUG RESISTANCE

Insight on ecDNA-mediated tumorigenesis and drug resistance

Extrachromosomal DNAs (ecDNAs) are a pervasive feature found in cancer and contain oncogenes and their corresponding regulatory elements.Their unique structural properties allow a rapid amplification of oncogenes and alter chromatin accessibility, leading to tumorigenesis and malignant development.The saosin baltimore uneven segregation of ecDNA du

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Nature vs. nurture is nonsense: On the necessity of an integrated genetic, social, developmental, and personality psychology

The field of behavioural genetics unambiguously demonstrates that heritable individual differences exist and are important in explaining human behaviour.Despite this, some psychological perspectives ignore this research.If we wish to comprehensively understand the impact of parenting, the environment, or any social factor, however, we must engage w

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